Job Summary:

This position works in the Cheryl Ackert-Bicknell Laboratory, under Cheryl Ackert-Bicknell, PhD.

We focus on the genetic regulation of bone mass and the genetic causes of bone disease from the point of view of bone formation and strength. We use both forward and reverse genetics studies to interrogate the genetic causes of phenotypes critical to understanding bone quality that cannot be readily studied in human populations. These phenotypes of interest include bone composition, bone formation and mineralization by the osteoblast. In addition, we participate in many human cohort studies aimed at understanding the etiology of musculoskeletal disease wherein we determine the biological function of genes found to be associated with musculoskeletal traits. Lastly, we study the diagnosis of and the consequences of postoperative infection, with an emphasis on an infection associated with spinal instrumentation.

Key Responsibilities:

• Mouse husbandry, genotyping, skeletal and non-skeletal tissue harvest.
• Collection of skeletal imaging information from live mice and harvested tissue samples
• Isolation and purification of protein and nucleic acid from harvested tissues from mice and humans
• Molecular analyses of mouse and human tissues, including Western blotting, qPCR/PCR, immunohistochemistry and immunofluorescence
• Culture of primary cells and established cell lines. Transfection of cells with viral vectors or plasmid vectors.
• Histology of musculoskeletal tissues (rodent and human), including embedding, sectioning and imaging.

Why Join Us:

CU Medicine Orthopedics has an expert team of Orthopedic providers that consists of fellowship-trained surgeons and specialists who provide the highest quality, comprehensive care for your orthopedic needs. Using cutting-edge technology and minimally invasive techniques, we offer access to the most advanced procedures to get you back to your life as quickly as possible. From foot and ankle issues to total replacements along with spine and sports medicine injuries, we provide full-service orthopedic care. We also have providers who specialize in pediatric orthopedics to treat younger patients with customized care.

The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off - vacation, sick, and holidays and more. To see what benefits are available, please visit: https://www.cu.edu/employee-services/benefits-wellness.

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

Entry Professional Level:

• Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
  • A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis

Intermediate Professional Level:

• Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
  • A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
• One (1) year professional level research experience

Senior Professional Level:

• Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
  • A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
• Two (2) years professional level research experience

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• 3+ years of experience working in a molecular biology lab or equivalent research experience.
• Experience with culture of primary mammalian cells and cell lines is required.
• 1+ years of experience working with laboratory mice.

Knowledge, Skills and Abilities:

• Understanding of skeletal physiology and genetics
• Ability to work both in a team environment and independently.
• Strong organizational and record-keeping skills
• Strong communication skills, both verbal and written
• Computer skills in both Mac and PC environments and use of standard programs such as Word and Excel
• Bioinformatics and or programming expertise in languages such as R, Python or Matlab would be a plus

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Thomas Roller, THOMAS.ROLLER@CUANSCHUTZ.EDU

Screening of Applications Begins:

Screening begins one to two weeks after posting and continues until position is filled.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as

Entry: $45,000 - $57,240

Intermediate: $48,970 - $62,290

Senior: $52,941 - $67,341

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date. Information regarding this requirement, and exemptions can be found at:

Anschutz: https://www.ucdenver.edu/docs/librariesprovider284/default-document-library/3000-general-admission/3012a---covid-19-vaccination-requirement-and-compliance.pdf?sfvrsn=b1e0ccba_10

Unit-Specific Exemptions:

• Anschutz Campus - Accommodations may be granted for medical or religious reasons.

The University of Colorado seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.